Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953638 | 0.88 | HRH3 (0.40) | KMT2AMEN1ALDH1A1NR4A2MAOB | |
| SCHEMBL21051406 | 0.84 | NR4A1 (0.57) | KMT2AMEN1ALDH1A1NR4A2MAOB | |
| SCHEMBL8953782 | 0.83 | MAOB (0.40) | KMT2ANR4A2MAOB | |
| SCHEMBL8408804 | 0.82 | F10 (0.53) | — | |
| SCHEMBL8953811 | 0.81 | ALOX5 (0.40) | KMT2AMAOB | |
| SCHEMBL8306162 | 0.79 | MEN1 (0.79) | KMT2AMEN1NR4A2MAOBNR4A1 | |
| SCHEMBL9310760 | 0.77 | ALOX5 (0.66) | — | |
| SCHEMBL9307584 | 0.77 | ALOX5 (0.49) | KMT2AMEN1NR4A2MAOB | |
| SCHEMBL8953658 | 0.77 | HSD11B1 (0.37) | ALDH1A1KAT6AKDM2B | |
| SCHEMBL16115550 | 0.77 | KMT2A (0.60) | KMT2AMEN1NR4A2MAOBNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |