Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308573 | 0.89 | KMT2A (0.50) | MAOBMRGPRX4RAB9A | |
| SCHEMBL9307724 | 0.86 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9307584 | 0.80 | ALOX5 (0.49) | ALOX5MAOBMRGPRX4RAB9A | |
| SCHEMBL9000918 | 0.76 | ALOX5 (0.46) | ALOX5MAOBMRGPRX4RAB9A | |
| SCHEMBL9221371 | 0.72 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9081307 | 0.71 | ALOX5 (0.52) | ALOX5MRGPRX4RAB9A | |
| SCHEMBL26358151 | 0.70 | MEN1 (0.73) | ALOX5MRGPRX4RAB9A | |
| SCHEMBL9228198 | 0.70 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9229588 | 0.69 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9370131 | 0.69 | CASP3 (0.51) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |