Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828137 | 0.96 | HTT (0.56) | HTTKMT2AOPRM1ALDH1A1ATM | |
| SCHEMBL11186607 | 0.93 | OPRM1 (0.51) | HTTOPRM1ALDH1A1NAAA | |
| SCHEMBL9831112 | 0.88 | OPRM1 (0.50) | HTTOPRM1FFAR1 | |
| SCHEMBL9308871 | 0.84 | NAAA (0.51) | HTTKMT2AOPRM1ALDH1A1LMNA | |
| SCHEMBL21798492 | 0.82 | EPHX2 (0.60) | KMT2AALDH1A1 | |
| SCHEMBL27884835 | 0.81 | FFAR1 (0.49) | MAPK1ALDH1A1ADRA1ALMNAFFAR1 | |
| SCHEMBL10639479 | 0.81 | OPRM1 (0.51) | OPRM1LMNANAAA | |
| SCHEMBL9293279 | 0.80 | OPRM1 (0.50) | HTTOPRM1ALDH1A1NAAA | |
| SCHEMBL17550883 | 0.80 | OPRM1 (0.50) | OPRM1LMNANAAA | |
| SCHEMBL19182 | 0.79 | FFAR1 (0.50) | MAPK1ALDH1A1ADRA1AFFAR1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |