Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308366 | 0.92 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL9305414 | 0.83 | ELANE (0.45) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL9307464 | 0.75 | ALPG (0.46) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL28673639 | 0.73 | ALPG (0.59) | ALDH1A1L3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL9306891 | 0.72 | SMN1; SMN2 (0.60) | ALDH1A1L3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL9306095 | 0.71 | ALPG (0.60) | ALDH1A1L3MBTL1KDM4EMAPTATM | |
| SCHEMBL9305135 | 0.70 | MAPT (0.46) | ALDH1A1L3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL2116682 | 0.69 | TP53 (0.46) | ALDH1A1L3MBTL1KDM4EMAPTHSD17B10 | |
| SCHEMBL9306916 | 0.69 | NTRK1 (0.51) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9307409 | 0.68 | HSD17B10 (0.60) | ALDH1A1L3MBTL1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340808-A | Fused pyridazinoquinazolone derivatives as neurotrophic agents | WARNER LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |