Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NGFR | P08138 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309118 | 0.84 | NTRK1 (0.39) | SCDBCHEACHENTRK1NGFR | |
| SCHEMBL9306771 | 0.79 | NTRK1 (0.59) | NTRK1NGFRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9305847 | 0.75 | HSD17B10 (0.43) | NPC1RAB9ASMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL9306694 | 0.75 | SMN1; SMN2 (0.53) | NPC1RAB9ASMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL9307464 | 0.74 | ALPG (0.46) | NPC1RAB9ASMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL9306949 | 0.73 | P4HTM (0.51) | NTRK1NGFRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9306891 | 0.73 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9306095 | 0.72 | ALPG (0.60) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9306208 | 0.72 | NTRK1 (0.48) | NTRK1NGFRRXFP1NPC1RAB9A | |
| SCHEMBL9306916 | 0.72 | NTRK1 (0.51) | NTRK1NGFRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340808-A | Fused pyridazinoquinazolone derivatives as neurotrophic agents | WARNER LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |