Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306776 | 0.81 | MAPT (0.47) | NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11151289 | 0.74 | ATM (0.56) | NPC1MITFLMNAPOLBALDH1A1 | |
| SCHEMBL9309137 | 0.74 | PBRM1 (0.46) | NPC1MITFLMNAPOLBPBRM1 | |
| SCHEMBL4444843 | 0.73 | GABRA1 (0.47) | NPC1ALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL6160025 | 0.73 | MAPK1 (0.60) | PBRM1ALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL31570061 | 0.72 | NPC1 (1.00) | NPC1MITFLMNAPOLBPBRM1 | |
| SCHEMBL6158282 | 0.71 | ALDH1A1 (0.45) | NPC1MITFLMNAPOLBPBRM1 | |
| SCHEMBL125621 | 0.71 | PBRM1 (0.87) | NPC1MITFLMNAPOLBPBRM1 | |
| SCHEMBL29363032 | 0.71 | PBRM1 (0.87) | NPC1MITFLMNAPOLBPBRM1 | |
| SCHEMBL9282073 | 0.71 | PBRM1 (0.87) | NPC1MITFLMNAPOLBPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308754-A | Terbium compounds | KANKARE JOUKO J | 1994-05-03 | — | — | US | disclosed |