Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309149 | 0.81 | NPC1 (0.55) | ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9306766 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL6160168 | 0.75 | RAB9A (0.66) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8720282 | 0.75 | MEN1 (0.58) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL7787691 | 0.75 | ALDH1A1 (0.74) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL6158148 | 0.74 | KMT2A (0.57) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL181572 | 0.74 | CES2 (0.78) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL10539201 | 0.73 | KMT2A (0.62) | MAPTALDH1A1CES2CES1KMT2A | |
| SCHEMBL11593026 | 0.72 | CES2 (0.76) | ALDH1A1CES2CES1KMT2AMEN1 | |
| Malonic Acid Diethyl Ester SCHEMBL27871201 | 0.72 | MEN1 (0.58) | MAPTALDH1A1CES2CES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308754-A | Terbium compounds | KANKARE JOUKO J | 1994-05-03 | — | — | US | disclosed |