Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | OGT | O15294 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7293222 | 0.99 | GRIN2B (0.47) | GRIN2BKCNH2GAAMEN1KMT2A | |
| SCHEMBL7366835 | 0.84 | NPY2R (0.49) | KMT2ACHRM3 | |
| SCHEMBL7295719 | 0.75 | KIF11 (0.41) | ALDH1A1TBXAS1PDE3BPDE3A | |
| SCHEMBL9561851 | 0.74 | GRIN2B (0.56) | GRIN2BKCNH2GAAMEN1KMT2A | |
| SCHEMBL7315170 | 0.74 | CRBN (0.53) | GRIN2BKCNH2GAAMEN1KMT2A | |
| SCHEMBL466863 | 0.73 | GRIN2B (0.61) | GRIN2BKCNH2MEN1KMT2AOGT | |
| SCHEMBL9562478 | 0.72 | GRIN2B (0.60) | GRIN2BKCNH2MEN1KMT2AOGT | |
| Hydrochloric Acid SCHEMBL7370551 | 0.71 | TSHR (0.40) | KCNH2ALDH1A1PDE3BPDE3A | |
| SCHEMBL7307710 | 0.70 | LMNA (0.50) | KMT2ACHRM3OPRM1 | |
| SCHEMBL5467351 | 0.70 | KCNH2 (0.55) | GRIN2BKCNH2GAAALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |