Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316521 | 0.84 | FGFR3 (0.34) | ARPGRIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL9308252 | 0.83 | TSHR (0.37) | ALDH1A1GAATSHRKDM4EHPGD | |
| SCHEMBL9309638 | 0.81 | PTGES (0.36) | ALDH1A1GAATSHRKDM4EHPGD | |
| SCHEMBL9308818 | 0.79 | KDM4E (0.34) | ARALDH1A1GAATSHRKDM4E | |
| SCHEMBL9309957 | 0.78 | MAPT (0.41) | ALDH1A1TSHRKDM4EHPGDMEN1 | |
| SCHEMBL9312060 | 0.78 | AR (0.39) | ARPGRALDH1A1GAATSHR | |
| SCHEMBL9309635 | 0.75 | CSNK2A2 (0.40) | ALDH1A1TSHRKDM4EHPGDMEN1 | |
| SCHEMBL9308247 | 0.74 | KCNH2 (0.46) | ALDH1A1TSHRKDM4EHPGDMEN1 | |
| SCHEMBL8550394 | 0.71 | TSHR (0.36) | ALDH1A1GAATSHRKDM4EHPGD | |
| SCHEMBL9308810 | 0.70 | KDM4E (0.38) | ALDH1A1TSHRKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |