Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563372 | 0.81 | KDM4E (0.37) | ALDH1A1MAPTLMNAMAPK14HPGD | |
| SCHEMBL4370028 | 0.75 | ADORA1 (0.41) | ALDH1A1 | |
| SCHEMBL1665498 | 0.73 | PARP1 (0.42) | — | |
| SCHEMBL4362603 | 0.72 | KDM4C (0.42) | KDM4C | |
| SCHEMBL4370037 | 0.72 | NOS2 (0.41) | KDM4CKDM4EMAPK1 | |
| SCHEMBL12799133 | 0.72 | NUDT1 (0.41) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL14336690 | 0.71 | CCR1 (0.35) | — | |
| SCHEMBL3948888 | 0.71 | ADORA3 (0.34) | KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL21620891 | 0.70 | NOS3 (0.41) | — | |
| SCHEMBL21620456 | 0.70 | CCNB2 (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354759-A | Angiotenin II antagonizing heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0553682-A1 | Imidazo 4,5-b pyridine derivatives as Angiotensin II antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |