Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433547 | 0.91 | THRA (0.34) | HPGDRAB9ATHRB | |
| SCHEMBL11498943 | 0.89 | THRB (0.36) | KDM4EALDH1A1THRB | |
| SCHEMBL9311943 | 0.86 | NOS2 (0.39) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9310987 | 0.84 | NOS3 (0.31) | NOS2 | |
| SCHEMBL27343969 | 0.83 | TAAR1 (0.36) | — | |
| SCHEMBL17160001 | 0.83 | KDM4E (0.32) | NOS2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9312352 | 0.83 | KDM4E (0.37) | NOS2KDM4EALDH1A1GAAHPGD | |
| Ammonia Solution, Strong SCHEMBL22472015 | 0.82 | — | — | |
| SCHEMBL2222701 | 0.78 | — | — | |
| SCHEMBL9310858 | 0.77 | TSHR (0.38) | NOS2KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630752-B1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-30 | — | — | EP | disclosed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |