Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017543 | 0.94 | DHODH (0.65) | DHODHEPHX2TP53MAPK10CYP2C9 | |
| SCHEMBL9017564 | 0.94 | DHODH (0.61) | DHODHEPHX2TP53RAB9AMAPT | |
| SCHEMBL9017562 | 0.90 | DHODH (0.59) | DHODHEPHX2TP53MAPK10CYP2C9 | |
| SCHEMBL9017616 | 0.90 | DHODH (0.59) | DHODHEPHX2TP53MAPK10CYP2C9 | |
| SCHEMBL27242987 | 0.87 | DHODH (0.74) | DHODHTP53MAPK10CYP2C9CYP2C19 | |
| SCHEMBL25813258 | 0.87 | DHODH (0.74) | DHODHTP53MAPK10CYP2C9CYP2C19 | |
| SCHEMBL9157076 | 0.85 | DHODH (0.64) | DHODHEPHX2TP53RAB9AMAPT | |
| SCHEMBL8614830 | 0.84 | DHODH (0.69) | DHODHTP53MAPK10CYP2C9CYP2C19 | |
| SCHEMBL9017605 | 0.83 | DHODH (0.61) | DHODHEPHX2RAB9AMAPTMAPK1 | |
| SCHEMBL9017561 | 0.83 | DHODH (0.61) | DHODHEPHX2GAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312830-A | Antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1994-05-17 | — | — | US | disclosed |