SCHEMBL13857069

SCHEMBL13857069

ClCc1cccc(Cc2cccc(CCl)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
CALM1 P0DP23 1/20 0.43
IDH1 O75874 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
CYP3A4 P08684 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PNMT P11086 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP1B1 Q16678 1/20 0.34
TAAR1 Q96RJ0 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430949 0.93 CALM1 (0.57) TSHRCALM1IDH1PRSS1PRSS2
SCHEMBL225197 0.91 TSHR (0.54) TSHRCALM1CYP3A4MEN1KMT2A
SCHEMBL13857073 0.87 TSHR (0.44) TSHRCALM1TAAR1
SCHEMBL10877973 0.87 TAAR1 (0.48) TSHRIDH1MEN1KMT2ATAAR1
SCHEMBL9311601 0.83 TSHR (0.48) TSHRMEN1KMT2ATAAR1
SCHEMBL25406688 0.79 TSHR (0.48) TSHRMEN1KMT2APNMTCYP1A1
SCHEMBL23892201 0.79 PNMT (0.60) TSHRCYP3A4PNMTTAAR1LOXL2
SCHEMBL8733207 0.79 TP53 (0.48) TSHRCYP1A2
SCHEMBL7713859 0.79 ENPP2 (0.50) TSHRPRSS1PRSS2PRSS3
SCHEMBL10401414 0.79 TSHR (0.45) TSHRCYP3A4MEN1KMT2APNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923418-B1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2016-11-09 EP disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed