SCHEMBL9312129

SCHEMBL9312129

[CH2]CCSCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
THRB P10828 2/20 0.46
GMNN O75496 1/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
BLM P54132 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 1/20 0.45
TSHR P16473 3/20 0.42
FAAH O00519 4/20 0.41
CES1 P23141 4/20 0.41
PLA2G6 O60733 1/20 0.41
PRKD3 O94806 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
PRKCA P17252 2/20 0.37
PRKCH P24723 2/20 0.37
PRKCI P41743 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5892194 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7838993 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL16892523 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL11692190 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7839304 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL9312687 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7829248 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL11529157 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL5042153 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL17415841 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338642-A Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US claimed
CN-118317944-A Acyclic lipids and methods of use thereof 雷纳嘉德医疗管理公司 2024-07-09 CN disclosed
CN-118234707-A Cyclic lipids and methods of use thereof 雷纳嘉德医疗管理公司 2024-06-21 CN disclosed
US-10548911-B2 Small molecule anti-scarring agents UNIVERSITY OF ROCHESTER (US) 2020-02-04 US disclosed
EP-2894685-B1 BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR DAINIPPON INK & CHEMICALS (JP) 2018-10-31 EP disclosed
EP-2978768-B1 CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2017-11-29 EP disclosed
US-20170216332-A1 SMALL MOLECULE ANTI-SCARRING AGENTS UNIVERSITY OF ROCHESTER (US) 2017-08-03 US disclosed
US-20170204076-A1 SYNTHESIS AND USE OF AMINO LIPIDS SCREENFECT GMBH (DE) 2017-07-20 US disclosed
US-9490433-B2 Benzothienobenzothiophene derivative, organic semiconductor material, and organic transistor DIC CORPORATION (JP) 2016-11-08 US disclosed
EP-2978768-A1 CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE Momentive Performance Materials Inc. (US) 2016-02-03 EP disclosed
US-4322527-A 6-Amino-dibenz[d,g][1,3,2]dioxaphosphocines CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed
US-4301061-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1981-11-17 US disclosed
US-4297492-A STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1981-10-27 US disclosed
EP-0005500-B1 DIOXAPHOSPHEPINES, THEIR PREPARATION AND USE AS STABILISERS FOR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1981-10-07 EP disclosed
US-4259492-A STABILIZERS FOR PLASTICS AND ELASTOMERS CIBA-GEIGY CORPORATION (US) 1981-03-31 US disclosed
EP-0020297-A1 Cyclic phosphoric acid ester amides, process for their preparation and their use as stabilizers CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
EP-0007758-A1 Alkyl ammonium ionomers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-02-06 EP disclosed
EP-0005441-A1 Aminodibenzoxaphosphorines, process for their preparation and their use as stabilisators CIBA-GEIGY AG (CH) 1979-11-28 EP disclosed
EP-0005500-A1 Dioxaphosphepines, their preparation and use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1979-11-28 EP disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170216332-A1 SMALL MOLECULE ANTI-SCARRING AGENTS COLGALT1, MMP1, FIBP CES2 2403/4885THRB 2211/4885GMNN 3176/4885
US-10548911-B2 Small molecule anti-scarring agents COLGALT1, MMP1, FIBP CES2 2403/4885THRB 2211/4885GMNN 3176/4885
US-20170204076-A1 SYNTHESIS AND USE OF AMINO LIPIDS ACSL4, PYM1, LPAR4 CES2 879/4885THRB 3696/4885GMNN 1832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.