SCHEMBL5042153

SCHEMBL5042153

[CH2]CCSCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
THRB P10828 2/20 0.46
GMNN O75496 1/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
BLM P54132 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 1/20 0.45
TSHR P16473 3/20 0.42
FAAH O00519 4/20 0.41
CES1 P23141 4/20 0.41
PLA2G6 O60733 1/20 0.41
PRKD3 O94806 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
PRKCA P17252 2/20 0.37
PRKCH P24723 2/20 0.37
PRKCI P41743 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5892194 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7838993 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL9312129 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL16892523 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL11692190 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7839304 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL9312687 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL7829248 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL11529157 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB
SCHEMBL17415841 1.00 CES2 (0.46) CES2THRBGMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2894685-B1 BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR DAINIPPON INK & CHEMICALS (JP) 2018-10-31 EP disclosed
US-9490433-B2 Benzothienobenzothiophene derivative, organic semiconductor material, and organic transistor DIC CORPORATION (JP) 2016-11-08 US disclosed
US-20150228913-A1 BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR DIC CORPORATION (JP) 2015-08-13 US disclosed
EP-2894685-A1 BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR DIC Corporation (JP) 2015-07-15 EP disclosed
EP-1282605-B1 THIOIMIDAZOLIDINE DERIVATIVES AS LIGHT STABILISERS FOR POLYMERS CIBA SC HOLDING AG (CH) 2008-01-02 EP disclosed
US-7153973-B2 Imidazolidinone derivatives CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-26 US disclosed
EP-1016661-B1 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AS AGRICULTURAL CHEMICALS DAINIPPON INK & CHEMICALS (JP) 2005-08-03 EP disclosed
US-6924330-B2 Thioimidazolidine derivatives as light stabilizers for polymers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-08-02 US disclosed
US-20050038236-A1 Imidazolidinone derivatives LAZZARI DARIO (IT) 2005-02-17 US disclosed
US-20030109609-A1 Thioimidazolidine derivatives as light stabilizers for polymers CIBA SPECIALTY CHEMICALS CORP. 2003-06-12 US disclosed
EP-0751133-A1 Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-02 EP disclosed
US-5516914-A Compositions stabilized with 5-thio-substituted benzotriazole UV-absorbers CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US disclosed
US-5280124-A Having a phenol structure in position 2 CIBA-GEIGY CORPORATION (US) 1994-01-18 US disclosed
US-5278314-A N-Phenol-substituted benzotriazoles CIBA-GEIGY CORPORATION (US) 1994-01-11 US disclosed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP disclosed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP disclosed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed
EP-0042359-B1 PHOSPHONOUS-ACID MONOESTER MONOAMIDE AND ORGANIC POLYMERS STABILIZED THEREWITH CIBA-GEIGY AG (CH) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038236-A1 Imidazolidinone derivatives C9, CBR1, GCN1 CES2 2080/4885THRB 1670/4885GMNN 259/4885
US-20150228913-A1 BENZOTHIENOBENZOTHIOPHENE DERIVATIVE, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC TRANSISTOR TST, TPST2, TPR CES2 3225/4885THRB 1550/4885GMNN 2549/4885
US-20030109609-A1 Thioimidazolidine derivatives as light stabilizers for polymers CCT4, GCN1, CBR1 CES2 2220/4885THRB 3516/4885GMNN 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.