Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 12/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SELL | P14151 | 2/20 | 0.42 |
| ▸ | SELP | P16109 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | FUT4 | P22083 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168968 | 1.00 | RECQL (0.50) | RECQLKDM1AKDM4ELMNATDP1 | |
| SCHEMBL18717467 | 1.00 | RECQL (0.50) | RECQLKDM1AKDM4ELMNATDP1 | |
| Hydrochloric Acid SCHEMBL4170165 | 0.98 | RECQL (0.48) | RECQLKDM1AKDM4ELMNATDP1 | |
| SCHEMBL31716495 | 0.81 | KDM1A (0.46) | RECQLKDM1ALMNAGAAL3MBTL1 | |
| SCHEMBL8121974 | 0.78 | TTR (0.48) | RECQLKDM1AALDH1A1HPGDMAPK1 | |
| SCHEMBL12433083 | 0.76 | KDM1A (0.65) | RECQLKDM1AKDM4EMAPTCA12 | |
| SCHEMBL1338635 | 0.76 | LMNA (0.44) | RECQLKDM1AKDM4ELMNAALDH1A1 | |
| SCHEMBL3237528 | 0.76 | TTR (0.46) | RECQLKDM1ALMNATDP1ALDH1A1 | |
| SCHEMBL1338633 | 0.76 | LMNA (0.44) | RECQLKDM1AKDM4ELMNAALDH1A1 | |
| SCHEMBL3237533 | 0.76 | TTR (0.46) | RECQLKDM1ALMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248782-B1 | ADMINISTERING ENZYME INHIBITOR | ELFORD HOWARD L (US) | 2001-06-19 | — | — | US | claimed |
| EP-0610444-A4 | METHOD OF TREATING VIRAL DISEASES. | ELFORD HOWARD L (US) | 1995-05-17 | — | — | EP | claimed |
| EP-0610444-A1 | METHOD OF TREATING VIRAL DISEASES | ELFORD, Howard L. (US) | 1994-08-17 | — | — | EP | claimed |
| WO-1993012782-A1 | METHOD OF TREATING VIRAL DISEASES | ELFORD HOWARD L (US) | 1993-07-08 | — | — | WO | claimed |
| EP-0144396-B1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | VAN'T RIET, Bartholomeus (US) | 1991-01-02 | — | — | EP | claimed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | claimed |
| EP-0144396-A4 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1986-08-21 | — | — | EP | claimed |
| EP-0144396-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1985-06-19 | — | — | EP | claimed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | claimed |
| US-20250092032-A1 | DEOXYCYTIDINE KINASE INHIBITORS | INSTITUT JEAN PAOLI & IRENE CALMETTES CENTRE REGIONAL DE LUTTE CONTRE LE CANCER (FR) | 2025-03-20 | — | — | US | disclosed |
| US-20240074995-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FIRST WAVE BIO, INC. | 2024-03-07 | — | — | US | disclosed |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11744812-B2 | Methods of treatment | FIRST WAVE BIO, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| WO-2023135330-A1 | DEOXYCYTIDINE KINASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-07-20 | — | — | WO | disclosed |
| EP-0144396-B1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | VAN'T RIET, Bartholomeus (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0144396-A4 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0144396-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES. | RIET BARTHOLOMEUS VAN T (US) | 1985-06-19 | — | — | EP | disclosed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240074995-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FH, CS, ECHS1 | RECQL 2170/4885KDM1A 3123/4885KDM4E 2452/4885 |
| US-11744812-B2 | Methods of treatment | ACE2, ACE, SI | RECQL 920/4885KDM1A 3615/4885KDM4E 3249/4885 |
| US-20250092032-A1 | DEOXYCYTIDINE KINASE INHIBITORS | DCK, DTYMK, TYMP | RECQL 1013/4885KDM1A 802/4885KDM4E 689/4885 |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FH, CS, ECHS1 | RECQL 2203/4885KDM1A 3251/4885KDM4E 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.