SCHEMBL4168968

SCHEMBL4168968

N/C(=N\O)c1cc(O)c(O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 3/20 0.50
KDM1A O60341 12/20 0.44
KDM4E B2RXH2 4/20 0.42
LMNA P02545 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 3/20 0.42
FUT7 Q11130 2/20 0.42
TP53 P04637 2/20 0.42
HPGD P15428 2/20 0.42
MAPK1 P28482 2/20 0.42
HSD17B10 Q99714 2/20 0.42
SELL P14151 2/20 0.42
SELP P16109 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
FUT4 P22083 1/20 0.42
CA4 P22748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4168972 1.00 RECQL (0.50) RECQLKDM1AKDM4ELMNATDP1
SCHEMBL18717467 1.00 RECQL (0.50) RECQLKDM1AKDM4ELMNATDP1
Hydrochloric Acid SCHEMBL4170165 0.98 RECQL (0.48) RECQLKDM1AKDM4ELMNATDP1
SCHEMBL31716495 0.81 KDM1A (0.46) RECQLKDM1ALMNAGAAL3MBTL1
SCHEMBL8121974 0.78 TTR (0.48) RECQLKDM1AALDH1A1HPGDMAPK1
SCHEMBL12433083 0.76 KDM1A (0.65) RECQLKDM1AKDM4EMAPTCA12
SCHEMBL1338635 0.76 LMNA (0.44) RECQLKDM1AKDM4ELMNAALDH1A1
SCHEMBL3237528 0.76 TTR (0.46) RECQLKDM1ALMNATDP1ALDH1A1
SCHEMBL1338633 0.76 LMNA (0.44) RECQLKDM1AKDM4ELMNAALDH1A1
SCHEMBL3237533 0.76 TTR (0.46) RECQLKDM1ALMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US claimed
EP-4593859-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION Eresina, LLC (US) 2025-08-06 EP claimed
WO-2024073011-A1 TOPICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO claimed
WO-2024073013-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO claimed
US-11773098-B2 Solid forms of a toll-like receptor modulator GILEAD SCIENCES, INC. (US) 2023-10-03 US claimed
CN-122055367-A 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors 皮卡维森治疗学股份有限公司 2026-05-15 CN disclosed
CN-122036801-A Crystalline forms of tenofovir alafenamide 吉利德科学公司 2026-05-15 CN disclosed
US-20260132122-A1 6-6-FUSED BICYCLIC HETEROARYL AMINES AS CDK4 INHIBITORS INCYTE CORP (US) 2026-05-14 US disclosed
US-20260125391-A1 PYRIMIDINE INDOLES AS CDK4 INHIBITORS INCYTE CORP (US) 2026-05-07 US disclosed
EP-4736856-A2 BICYCLIC AMINES AS CDK2 INHIBITORS Incyte Corporation (US) 2026-05-06 EP disclosed
EP-3870566-B1 PD-1/PD-L1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-06 EP disclosed
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
US-9526707-B2 Methods for treating or preventing neuroinflammation or autoimmune diseases ELFORD HOWARD L (US) 2016-12-27 US disclosed
US-9526707-B2 Methods for treating or preventing neuroinflammation or autoimmune diseases ELFORD HOWARD L (US) 2016-12-27 US disclosed
US-8932617-B2 Methods for treating or preventing restenosis and other vascular proliferative disorders ELFORD HOWARD L (US) 2015-01-13 US disclosed
EP-2030615-A2 Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases ELFORD, Howard L. (US) 2009-03-04 EP disclosed
EP-2030615-A2 Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases ELFORD, Howard L. (US) 2009-03-04 EP disclosed
US-20090047250-A1 Methods for treating or preventing neuroinflammation or autoimmune diseases ELFORD HOWARD L 2009-02-19 US disclosed
US-20090047250-A1 Methods for treating or preventing neuroinflammation or autoimmune diseases ELFORD HOWARD L 2009-02-19 US disclosed
US-20090047250-A1 Methods for treating or preventing neuroinflammation or autoimmune diseases ELFORD HOWARD L 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090047250-A1 Methods for treating or preventing neuroinflammation or autoimmune diseases RNASE1, RNASEH1, TXNRD3 RECQL 513/4885KDM1A 2112/4885KDM4E 3319/4885
US-20260132122-A1 6-6-FUSED BICYCLIC HETEROARYL AMINES AS CDK4 INHIBITORS CCNA1, CDK4, CCNO RECQL 716/4885KDM1A 1180/4885KDM4E 2159/4885
US-11773098-B2 Solid forms of a toll-like receptor modulator TLR4, TLR3, TLR6 RECQL 3078/4885KDM1A 3674/4885KDM4E 2774/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 RECQL 1167/4885KDM1A 2620/4885KDM4E 2468/4885
US-20260125391-A1 PYRIMIDINE INDOLES AS CDK4 INHIBITORS CDK4, CCNA1, CCNO RECQL 593/4885KDM1A 1447/4885KDM4E 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.