Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558862 | 0.85 | L3MBTL1 (0.44) | L3MBTL1KMT2AALDH1A1TSHRIDO1 | |
| SCHEMBL2466440 | 0.85 | L3MBTL1 (0.44) | L3MBTL1KMT2AALDH1A1TSHRIDO1 | |
| SCHEMBL15345312 | 0.77 | LOXL2 (0.45) | ALDH1A1TAAR1IDO1 | |
| SCHEMBL12983061 | 0.77 | CNR2 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL29926858 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRTAAR1IDO1 | |
| SCHEMBL3193406 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TSHRTAAR1IDO1 | |
| SCHEMBL29383544 | 0.75 | ALDH1A1 (0.39) | L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL2468219 | 0.75 | ALDH1A1 (0.39) | L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL9314804 | 0.74 | MAPT (0.39) | L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL7915217 | 0.74 | CYP2A6 (0.62) | L3MBTL1KMT2AALDH1A1TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34770-E | 1-benzothiophene derivatives; side effect reduction | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5334628-A | Amine derivatives, processes for preparing the same and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| US-5200423-A | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5106866-A | Skin disorders | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021458-A | Amine derivatives and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0164697-B1 | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-11-07 | — | — | EP | disclosed |
| CN-1007975-B | Process for the preparation of amine derivatives | KAKEN PHARMACEUFICAL CO LTD (JP) | 1990-05-16 | — | — | CN | disclosed |
| CN-1035771-A | Process for the preparation of amine derivatives and fungicides containing amine derivatives | SCIENT RESEARCH AND PHARMACEUT (JP) | 1989-09-27 | — | — | CN | disclosed |
| CN-85104330-A | Process for the preparation of amine derivatives and fungicides containing amine derivatives | — | 1986-12-03 | — | — | CN | disclosed |
| EP-0164697-A2 | Amine derivatives, processes for preparing the same and fungicides containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |