Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 12/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558449 | 1.00 | CASP1 (0.54) | CASP1CTRB1ATMTACR1CTSL | |
| SCHEMBL8458841 | 0.89 | CTRB1 (0.50) | CASP1CTRB1ATMTACR1CTSL | |
| SCHEMBL7296396 | 0.89 | CTRB1 (0.50) | CASP1CTRB1ATMTACR1CTSL | |
| SCHEMBL7418478 | 0.87 | TACR1 (0.55) | CASP1CTRB1TACR1CTSLCTSS | |
| SCHEMBL7298020 | 0.87 | CTRB1 (0.54) | CTRB1ATMTACR1CTSLCTSS | |
| SCHEMBL7300784 | 0.87 | CTRB1 (0.61) | CTRB1ATMTACR1CTSLCTSS | |
| SCHEMBL7172190 | 0.87 | CTRB1 (0.54) | CTRB1ATMTACR1CTSLCTSS | |
| SCHEMBL4598612 | 0.87 | CTRB1 (0.61) | CTRB1ATMTACR1CTSLCTSS | |
| SCHEMBL7169930 | 0.87 | CTRB1 (0.54) | CTRB1ATMTACR1CTSLCTSS | |
| SCHEMBL7310119 | 0.87 | CTRB1 (0.61) | CTRB1ATMTACR1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072015-B1 | METHOD FOR PURIFYING N-BENZYLOXYCARBONYL ASPARTIC ACID | PPG INDUSTRIES, INC. (US) | 1984-10-31 | — | — | EP | claimed |
| EP-0072015-A1 | Method for purifying N-benzyloxycarbonyl aspartic acid | PPG INDUSTRIES, INC. (US) | 1983-02-16 | — | — | EP | claimed |
| US-4350628-A | OXIDATIVE DEHYDROGENATION WITH A BENZOQUINONE | RESEARCH CORPORATION (US) | 1982-09-21 | — | — | US | claimed |
| CN-1129705-A | A method of preparing L-aspartyl-D-alpha-aminoalkanecarboxylic acid -(S)-N-alpha-alkylbenzylamide | AJINOMOTO KK (JP) | 1996-08-28 | — | — | CN | disclosed |
| US-5279946-A | Process for the preparation of N-benzyloxycarbonyl-alpha-L-aspartyl-L-phenylalanine methyl ester | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1994-01-18 | — | — | US | disclosed |
| EP-0550450-A1 | USE OF CROSSLINKED CRYSTALS AS A NOVEL FORM OF ENZYME IMMOBILIZATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992002617-A1 | USE OF CROSSLINKED CRYSTALS AS A NOVEL FORM OF ENZYME IMMOBILIZATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-02-20 | — | — | WO | disclosed |
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |