SCHEMBL9313779

SCHEMBL9313779

CCN(CP(=O)(O)O)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 2/20 0.42
LMNA P02545 2/20 0.42
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 5/20 0.40
CNR1 P21554 4/20 0.40
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
SSTR3 P32745 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9313842 0.81 TSHR (0.50) ALDH1A1MAPTGAAHTTRAB9A
Hydrochloric Acid SCHEMBL9314513 0.80 TSHR (0.48) ALDH1A1MAPTGAAHTTRAB9A
SCHEMBL6984098 0.78 ALDH1A1 (0.66) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL9313751 0.78 CA12 (0.39) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL9463877 0.73 MAPT (0.51) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL13181137 0.72 ALDH1A1 (0.59) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL15741279 0.72 ALDH1A1 (0.54) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL3069128 0.70 RAB9A (0.71) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL6443035 0.69 ALDH1A1 (0.51) ALDH1A1MAPTGAAMAPK1KDM4E
SCHEMBL5504743 0.69 MAPT (0.47) ALDH1A1MAPTGAAMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5315035-A Hydrogen peroxide detection BOEHRINGER MANNHEIM GMBH (DE) 1994-05-24 US claimed
EP-0175250-B1 AGENT AND PROCESS FOR THE DETERMINATION OF REDOX SYSTEMS Roche Diagnostics GmbH (DE) 1990-05-09 EP disclosed
US-4820632-A ANILINE DERIVATIVE AND OXIDIZABLE COUPLER COLORED COMPOUND FOR DETECTION OF HYDROGEN PEROXIDE; MEDICAL DIAGNOSIS BOEHRINGER MANNHEIM GMBH (DE) 1989-04-11 US disclosed
EP-0175250-A2 Agent and process for the determination of redox systems Roche Diagnostics GmbH (DE) 1986-03-26 EP disclosed