SCHEMBL9313751

SCHEMBL9313751

CN(CP(=O)(O)O)c1ccc(F)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
MMP2 P08253 1/20 0.39
APP P05067 2/20 0.37
KMT2A Q03164 1/20 0.36
FDPS P14324 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315794 0.81 ALDH1A1 (0.43) CA12MMP2KMT2AFDPSALDH1A1
SCHEMBL8801336 0.80 MEN1 (0.50) CA12KMT2AALDH1A1HTT
Hydrochloric Acid SCHEMBL8800744 0.78 MEN1 (0.48) CA12KMT2AALDH1A1HTT
SCHEMBL9313779 0.78 ALDH1A1 (0.50) CA12MMP2KMT2AALDH1A1KDM4E
SCHEMBL9313832 0.78 MMP13 (0.34) KMT2AMAPTMAPK1RAB9A
Phosphoric Acid SCHEMBL10591537 0.75 APP (0.57) APPKMT2AALDH1A1KDM4EGAA
SCHEMBL11584135 0.72 APP (0.40) APPKMT2AALDH1A1
SCHEMBL14364107 0.71 SLC6A9 (0.40) CA12APPALDH1A1KDM4E
SCHEMBL3706209 0.70 ADRA2A (0.48) APPKMT2AALDH1A1TAAR1ESR1
SCHEMBL27294764 0.69 L3MBTL1 (0.46) APPKMT2AALDH1A1TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5315035-A Hydrogen peroxide detection BOEHRINGER MANNHEIM GMBH (DE) 1994-05-24 US claimed
US-5315035-A Hydrogen peroxide detection BOEHRINGER MANNHEIM GMBH (DE) 1994-05-24 US disclosed
US-5084382-A A color former with an oxidizable coupler for detection of hydrogen peroxide or hydrogen peroxide forming system or peroxidase or oxidizers for amine detection BOEHRINGER MANNHEIM GMBH (DE) 1992-01-28 US disclosed
EP-0245802-B1 TEST DEVICE FOR DETERMINATION OF BLOOD CLOTTING PARAMETERS Roche Diagnostics GmbH (DE) 1991-09-18 EP disclosed
EP-0239002-B1 TEST SUPPORT AND METHOD FOR THE DETERMINATION OF COAGULATION PARAMETERS Roche Diagnostics GmbH (DE) 1990-09-26 EP disclosed
EP-0175250-B1 AGENT AND PROCESS FOR THE DETERMINATION OF REDOX SYSTEMS Roche Diagnostics GmbH (DE) 1990-05-09 EP disclosed
US-4910150-A In blood sample BOEHRINGER MANNHEIM GMBH (DE) 1990-03-20 US disclosed
EP-0208218-B1 COAGULATION-NEUTRAL, HYDROPHILIC GLASS FIBRES Roche Diagnostics GmbH (DE) 1990-03-07 EP disclosed
US-4861712-A Analysis element for determination of a coagulation parameter BOEHRINGER MANNEHEIM GMBH (DE) 1989-08-29 US disclosed
US-4820632-A ANILINE DERIVATIVE AND OXIDIZABLE COUPLER COLORED COMPOUND FOR DETECTION OF HYDROGEN PEROXIDE; MEDICAL DIAGNOSIS BOEHRINGER MANNHEIM GMBH (DE) 1989-04-11 US disclosed
US-4788152-A Apparatus for determining coagulation parameter BOEHRINGER MANNHEIM GMBH (DE) 1988-11-29 US disclosed
US-4786603-A COAGULATION TESTING BOEHRINGER MANNHEIM GMBH (DE) 1988-11-22 US disclosed
EP-0239002-A1 Test support and method for the determination of coagulation parameters Roche Diagnostics GmbH (DE) 1987-09-30 EP disclosed
EP-0175250-A2 Agent and process for the determination of redox systems Roche Diagnostics GmbH (DE) 1986-03-26 EP disclosed