Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472098 | 0.84 | MGLL (0.55) | MGLLROCK2TP53MAPTNPC1 | |
| SCHEMBL9312421 | 0.81 | NPC1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9313195 | 0.78 | MAPK14 (0.47) | SMN1; SMN2 | |
| SCHEMBL9312304 | 0.78 | GSK3B (0.53) | TP53MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9834136 | 0.76 | NQO2 (0.51) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL19224991 | 0.75 | MEN1 (0.70) | MGLLROCK2TP53MAPTNPC1 | |
| SCHEMBL10566416 | 0.74 | NPC1 (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10566414 | 0.74 | RAB9A (0.56) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL9313814 | 0.74 | MAOA (0.45) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL16374601 | 0.74 | MGLL (0.51) | MGLLROCK2TP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |