Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312900 | 0.94 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9312287 | 0.88 | FPR2 (0.54) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9866132 | 0.84 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9314396 | 0.79 | RARB (0.54) | MEN1KMT2AMAPTHDAC1HDAC2 | |
| SCHEMBL9313889 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL3150642 | 0.76 | HDAC3 (0.52) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31714495 | 0.76 | HDAC3 (0.52) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9314224 | 0.74 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9312531 | 0.74 | CNR1 (0.45) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9313377 | 0.74 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |