Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 5/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24249663 | 0.82 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL1187744 | 0.78 | KDM4E (0.80) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL11712509 | 0.78 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL31098995 | 0.78 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL9849561 | 0.76 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL8694650 | 0.76 | KDM4E (0.62) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL14451007 | 0.75 | NUDT1 (0.56) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL12763789 | 0.75 | TLR7 (0.66) | SMN1; SMN2MEN1KMT2AL3MBTL1ACP1 | |
| SCHEMBL1577669 | 0.75 | ALDH1A1 (0.63) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL20867956 | 0.75 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |