Sugi Predict

Sugi Predict / Compounds / SCHEMBL931458

SCHEMBL931458

SCHEMBL931458

Cc1ccc(S(=O)(=O)N2CC2c2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.78
▸ RAB9A P51151 1/20 0.78
▸ KMT2A Q03164 1/20 0.78
▸ NPSR1 Q6W5P4 1/20 0.68
▸ MMP2 P08253 1/20 0.59
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 3/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ GAA P10253 3/20 0.51
▸ TSHR P16473 2/20 0.51
▸ POLB P06746 1/20 0.49
▸ PSEN1 P49768 1/20 0.49
▸ PSEN2 P49810 1/20 0.49
▸ APH1B Q8WW43 1/20 0.49
▸ NCSTN Q92542 1/20 0.49
▸ APH1A Q96BI3 1/20 0.49
▸ PSENEN Q9NZ42 1/20 0.49
▸ MCOLN3 Q8TDD5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17970866 1.00 ALDH1A1 (0.78) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL31004048 0.94 ALDH1A1 (0.78) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL2600488 0.92 ALDH1A1 (0.64) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL17970865 0.92 ALDH1A1 (0.64) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL12615015 0.88 ALDH1A1 (1.00) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL18231514 0.88 NPSR1 (0.61) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL18231468 0.88 NPSR1 (0.61) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL6081314 0.86 ALDH1A1 (0.58) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL17970869 0.86 ALDH1A1 (0.58) ALDH1A1RAB9AKMT2ANPSR1MMP2
SCHEMBL15362303 0.86 NPSR1 (0.58) ALDH1A1RAB9AKMT2ANPSR1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108586738-B Synthesis method of linear polyethyleneimine segmented copolymer 南京工业大学 2020-10-27 — — CN claimed
JP-5032619-A — — None — — JP disclosed
CN-118459385-A Method for synthesizing 2-phenyl-1- (phenylsulfonyl) aziridine compound 常州大学 2024-08-09 — — CN disclosed
CN-112608269-B Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen 山东大学 2022-05-06 — — CN disclosed
CN-112608269-A Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen 山东大学 2021-04-06 — — CN disclosed
CN-108586738-B Synthesis method of linear polyethyleneimine segmented copolymer 南京工业大学 2020-10-27 — — CN disclosed
CN-104428331-B Active energy beam polymer resin composition and the laminated body for using the resin combination 东洋油墨SC控股株式会社 2019-02-15 — — CN disclosed
CN-104804004-B A kind of preparation method of chiral hexahydropyrrolo diindyl class compound 安徽师范大学 2017-03-29 — — CN disclosed
US-20160222423-A1 ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-08-04 — — US disclosed
US-20160222423-A1 ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-08-04 — — US disclosed
US-7662969-B2 Efficient aziridination of olefins catalyzed by dirhodium catalysts UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2010-02-16 — — US disclosed
CN-101607947-A A kind of preparation method of derivatives of tetrahydro triazine UNIV ZHEJIANG (CN) 2009-12-23 — — CN disclosed
WO-2009146032-A2 METAL PORPHYRIN CATALYZED OLEFIN AZIRIDINATION WITH SULFONYL AZIDES UNIVERSITY OF SOUTH FLORIDA (US) 2009-12-03 — — WO disclosed
US-20090093638-A1 Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2009-04-09 — — US disclosed
US-20090093638-A1 Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2009-04-09 — — US disclosed
WO-2009010129-A1 BISPIDON LIGANDS AND THE METAL COMPLEXES THEREOF Universität Heidelberg (DE) 2009-01-22 — — WO disclosed
WO-2009010129-A1 BISPIDON LIGANDS AND THE METAL COMPLEXES THEREOF Universität Heidelberg (DE) 2009-01-22 — — WO disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-5929252-A Aziridination of olefins THE SCRIPPS RESEARCH INSTITUTE (US) 1999-07-27 — — US disclosed
JP-H0532619-A PRODUCTION OF AZIRIDINE COMPOUND NIKKO KYODO CO LTD 1993-02-09 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG ALDH1A1 3259/4885RAB9A 4044/4885KMT2A 1748/4885
US-20090093638-A1 Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions CYP11B2, DHCR7, ZDHHC7 ALDH1A1 530/4885RAB9A 4875/4885KMT2A 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.