Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970865 | 1.00 | ALDH1A1 (0.64) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL6081489 | 0.92 | ALDH1A1 (0.73) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL6081660 | 0.92 | TRPA1 (0.58) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL6081299 | 0.92 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL17970867 | 0.92 | ALDH1A1 (0.73) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL17970866 | 0.92 | ALDH1A1 (0.78) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL931458 | 0.92 | ALDH1A1 (0.78) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL31004048 | 0.92 | ALDH1A1 (0.78) | ALDH1A1RAB9AKMT2ANPSR1MCOLN3 | |
| SCHEMBL17961631 | 0.89 | LMNA (0.64) | ALDH1A1RAB9AKMT2ANPSR1MAPT | |
| SCHEMBL6081340 | 0.89 | USP2 (0.55) | ALDH1A1RAB9AKMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222423-A1 | ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160222423-A1 | ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160222423-A1 | ENZYME-CATALYZED ENANTIOSELECTIVE AZIRIDINATION OF OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-08-04 | — | — | US | disclosed |
| CN-103087062-B | Method for preparing N-sulfonyl substituted tetrahydro-beta-carboline derivative | UNIV ANHUI NORMAL | 2015-06-03 | — | — | CN | disclosed |
| CN-103102304-B | Preparation method of N-sulfonyl substituted tetrahydroisoquinoline derivatives | UNIV ANHUI NORMAL | 2015-03-11 | — | — | CN | disclosed |
| CN-104193695-A | Synthesis method of morpholine compounds | HARBIN INST OF TECHNOLOGY | 2014-12-10 | — | — | CN | disclosed |
| CN-103102304-A | Preparation method of N-sulfonyl substituted tetrahydroisoquinoline derivatives | UNIV ANHUI NORMAL | 2013-05-15 | — | — | CN | disclosed |
| CN-103087062-A | Method for preparing N-sulfonyl substituted tetrahydro-beta-carboline derivative | UNIV ANHUI NORMAL | 2013-05-08 | — | — | CN | disclosed |
| US-8163944-B2 | Allylic oxidations catalyzed by dirhodium catalysts under aqueous conditions | UNIVERSITY OF MARYLAND COLLEGE PARK (US) | 2012-04-24 | — | — | US | disclosed |
| US-7662969-B2 | Efficient aziridination of olefins catalyzed by dirhodium catalysts | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2010-02-16 | — | — | US | disclosed |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-04-09 | — | — | US | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | PPOX, HCCS, ICOSLG | ALDH1A1 3259/4885RAB9A 4044/4885KMT2A 1748/4885 |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | CYP11B2, DHCR7, ZDHHC7 | ALDH1A1 530/4885RAB9A 4875/4885KMT2A 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.