Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695572 | 0.88 | ATM (0.44) | SMN1; SMN2ATMMAPTKDM4EALDH1A1 | |
| SCHEMBL9461991 | 0.77 | MEN1 (0.44) | ATMEPHX2KDM4EALDH1A1MEN1 | |
| SCHEMBL9462196 | 0.77 | MEN1 (0.44) | ATMEPHX2KDM4EALDH1A1MEN1 | |
| SCHEMBL2109163 | 0.76 | MCHR1 (0.44) | SMN1; SMN2ATMMAPTALDH1A1TDP1 | |
| SCHEMBL2112075 | 0.76 | MCHR1 (0.44) | SMN1; SMN2ATMMAPTALDH1A1TDP1 | |
| SCHEMBL9524914 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2ATMPPIDMMP8EPHX2 | |
| SCHEMBL8570991 | 0.74 | ALDH1A1 (0.41) | ATMMAPTELANEALDH1A1HSD17B10 | |
| SCHEMBL25346616 | 0.73 | SMN1; SMN2 (0.63) | SMN1; SMN2ATMPPIDMMP8EPHX2 | |
| SCHEMBL9805700 | 0.72 | CPB2 (0.33) | MMP8ALDH1A1 | |
| SCHEMBL9314368 | 0.72 | CPB2 (0.33) | MMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286721-A | Antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0506982-A1 | 1-AZABICYCLO 3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |