Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538756 | 1.00 | MAPT (0.47) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL9316426 | 0.85 | NPC1 (0.50) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL31538753 | 0.85 | NPC1 (0.50) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL11410414 | 0.85 | NFE2L2 (0.49) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL18241562 | 0.76 | G6PD (0.61) | MAPTNPC1RAB9AALDH1A1CA1 | |
| SCHEMBL9316413 | 0.74 | CA1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9315739 | 0.73 | MEN1 (0.54) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL28381130 | 0.72 | LMNA (0.51) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL28381129 | 0.72 | LMNA (0.51) | MAPTNPC1LMNARAB9ABCHE | |
| SCHEMBL17250800 | 0.72 | ALDH1A1 (0.61) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |