Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538748 | 1.00 | NFE2L2 (0.50) | NFE2L2NFKB1NFKB2RELABCHE | |
| SCHEMBL9321637 | 0.85 | XDH (0.57) | NFKB1NFKB2RELABCHECYP3A4 | |
| SCHEMBL9316470 | 0.85 | TP53 (0.50) | NFE2L2NFKB1NFKB2RELABCHE | |
| SCHEMBL31538747 | 0.85 | TP53 (0.50) | NFE2L2NFKB1NFKB2RELABCHE | |
| SCHEMBL31538752 | 0.83 | MAPT (0.49) | RELARAB9ANPC1PTPN1PTPN12 | |
| SCHEMBL9315516 | 0.83 | MAPT (0.49) | RELARAB9ANPC1PTPN1PTPN12 | |
| SCHEMBL9315739 | 0.82 | MEN1 (0.54) | NFE2L2RELABCHERAB9ANPC1 | |
| SCHEMBL31516468 | 0.76 | TTR (0.67) | NFE2L2NFKB1NFKB2RELABCHE | |
| SCHEMBL26643304 | 0.76 | TTR (0.67) | NFE2L2NFKB1NFKB2RELABCHE | |
| SCHEMBL9314769 | 0.76 | TSHR (0.50) | NFE2L2NFKB1NFKB2RELABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |