Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500735 | 0.85 | TSHR (0.64) | TSHRMAPK1ALDH1A1TDP1CA1 | |
| SCHEMBL487063 | 0.80 | ALDH1A1 (0.54) | TSHRALDH1A1TDP1CYP3A4CYP1A2 | |
| SCHEMBL3367391 | 0.78 | MAPT (0.56) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL15798372 | 0.72 | TSHR (0.46) | TSHRMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9017796 | 0.71 | TSHR (0.60) | TSHRMAPK1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL4298089 | 0.71 | VCAM1 (0.56) | TSHRMAPK1TDP1MAPTHSD17B10 | |
| SCHEMBL359179 | 0.71 | TSHR (0.67) | TSHRMAPK1ALDH1A1TDP1CA1 | |
| SCHEMBL31281371 | 0.71 | TSHR (0.67) | TSHRMAPK1ALDH1A1TDP1CA1 | |
| SCHEMBL3781263 | 0.68 | TSHR (0.60) | TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL11049733 | 0.68 | TSHR (0.65) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344898-A | Curable composition with stilbene groups and molecular orientation | THE DOW CHEMICAL COMPANY (US) | 1994-09-06 | — | — | US | disclosed |