⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118090 | 0.88 | — | — | |
| SCHEMBL16518077 | 0.88 | — | — | |
| SCHEMBL23743606 | 0.88 | — | — | |
| SCHEMBL16518072 | 0.83 | LGALS8 (0.32) | — | |
| SCHEMBL931603 | 0.83 | LGALS8 (0.32) | — | |
| SCHEMBL18652500 | 0.78 | GJB2 (0.38) | — | |
| SCHEMBL18652544 | 0.74 | FGF1 (0.36) | — | |
| SCHEMBL931718 | 0.72 | HPSE (0.34) | — | |
| SCHEMBL933072 | 0.72 | — | — | |
| SCHEMBL2527021 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448600-B1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2016-03-30 | — | — | EP | disclosed |
| US-8962573-B2 | Compounds targeting the cation-independent mannose 6-phosphate receptor | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2015-02-24 | — | — | US | disclosed |
| EP-2448600-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2012-05-09 | — | — | EP | disclosed |
| US-20120093795-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2012-04-19 | — | — | US | disclosed |
| WO-2011000958-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-01-06 | — | — | WO | disclosed |