Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 9/20 | 0.34 |
| ▸ | FGF1 | P05230 | 7/20 | 0.34 |
| ▸ | FGF2 | P09038 | 6/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932460 | 0.91 | HPSE (0.34) | HPSEFGF1FGF2VEGFATSHR | |
| SCHEMBL931717 | 0.88 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL2615800 | 0.79 | IARS1 (0.35) | HPSEFGF1FGF2MAPK1 | |
| SCHEMBL13273518 | 0.72 | GJB2 (0.42) | HPSEFGF1FGF2VEGFAMAPK1 | |
| SCHEMBL8429596 | 0.72 | CYP2D6 (0.53) | TSHRMAPK1 | |
| SCHEMBL8429599 | 0.72 | CYP2D6 (0.53) | TSHRMAPK1 | |
| SCHEMBL931604 | 0.72 | — | — | |
| SCHEMBL9472982 | 0.70 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL9472994 | 0.70 | ALDH1A1 (0.39) | TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL15316753 | 0.68 | MAPK1 (0.54) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448600-B1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2016-03-30 | — | — | EP | disclosed |
| US-8962573-B2 | Compounds targeting the cation-independent mannose 6-phosphate receptor | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2015-02-24 | — | — | US | disclosed |
| EP-2448600-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2012-05-09 | — | — | EP | disclosed |
| US-20120093795-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2012-04-19 | — | — | US | disclosed |
| WO-2011000958-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093795-A1 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | M6PR, IGF2R, MPI | HPSE 181/4885FGF1 2896/4885FGF2 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.