Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482488 | 0.83 | KDM4E (0.41) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL6559821 | 0.77 | KDM4E (0.37) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL8799390 | 0.75 | KDM4E (0.44) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL1171022 | 0.72 | KDM4E (0.45) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL19857472 | 0.72 | KDM4E (0.45) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL2486333 | 0.72 | KDM4E (0.41) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL1819716 | 0.71 | GABRP (0.44) | PARP1KDM4ETSHRALDH1A1MAPT | |
| SCHEMBL353523 | 0.71 | KDM4E (0.44) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL9684853 | 0.71 | ALDH1A1 (0.45) | KDM4ETSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL617721 | 0.71 | KDM4E (0.44) | KDM4ETSHRALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334576-A | Pre- and postemergence | AMERICAN CYANAMID COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0322616-A2 | Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1989-07-05 | — | — | EP | disclosed |