Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651894 | 0.88 | HDAC6 (0.35) | TIPARPHDAC6PIK3CGAOC3PDE4B | |
| SCHEMBL9844933 | 0.74 | HTR3A (0.33) | PIK3CACYP1A2CYP3A4HTR3A | |
| SCHEMBL30954833 | 0.73 | NAMPT (0.37) | TIPARPAOC3IRAK4NAMPT | |
| SCHEMBL27291990 | 0.70 | ELANE (0.40) | ELANETOP2ATOP2BPDE4BPDE4D | |
| SCHEMBL6530640 | 0.69 | KCNH2 (0.37) | — | |
| SCHEMBL9316471 | 0.67 | PIK3CG (0.65) | PIK3CGTOP2ATOP2BPIK3CACYP1A2 | |
| SCHEMBL10594808 | 0.66 | CYP11B2 (0.35) | TOP2ATOP2BCYP1A2CYP3A4HTR3A | |
| SCHEMBL9317503 | 0.66 | TOP2A (0.57) | PIK3CGTOP2ATOP2B | |
| SCHEMBL8589216 | 0.65 | ELANE (0.42) | ELANEPIK3CAPDE4BPDE4D | |
| SCHEMBL27283744 | 0.65 | DDB1 (0.40) | ELANEPDE4BPDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371090-A | Bactericides, feed additives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| US-5312823-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | disclosed |
| CN-1068114-A | 7-azepine iso-dihydro-indole-group-quinolone and naphthyridonecarboxylic derivative | BAYER AG (DE) | 1993-01-20 | — | — | CN | disclosed |