Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | LITAF | Q99732 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27283744 | 0.78 | DDB1 (0.40) | — | |
| SCHEMBL6052822 | 0.78 | PER2 (0.37) | ALDH1A1OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL10594808 | 0.76 | CYP11B2 (0.35) | HTR3ACYP1A2CYP2C9TSHRCYP3A4 | |
| SCHEMBL27291683 | 0.75 | OPRM1 (0.38) | TSHRCYP11B2OPRL1OPRM1OPRD1 | |
| SCHEMBL9014024 | 0.74 | PRKD3 (0.40) | CYP1A2CYP2C9ALDH1A1PIK3CACYP11B2 | |
| SCHEMBL9316462 | 0.74 | TIPARP (0.35) | HTR3ACYP1A2CYP3A4PIK3CA | |
| SCHEMBL29086080 | 0.74 | — | — | |
| SCHEMBL30585821 | 0.74 | — | — | |
| SCHEMBL10574955 | 0.73 | EZH2 (0.33) | HTR3ACYP1A2ALDH1A1TNFLITAF | |
| SCHEMBL15134878 | 0.73 | PDE2A (0.36) | CYP1A2ALDH1A1OPRM1OPRD1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424850-A1 | Quinolone compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |