4-Chloro-Benzoic Acid

4-Chloro-Benzoic Acid

SCHEMBL9316888

CC(=S)Nc1ccccc1.O=C(O)c1ccc(Cl)cc1.[PbH2]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R38 P59533 1/20 0.59
ALDH1A1 P00352 5/20 0.58
CYP19A1 P11511 2/20 0.56
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
EPHX1 P07099 3/20 0.50
NOX1 Q9Y5S8 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
POLB P06746 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
NLRP1 Q9C000 1/20 0.49
SRD5A2 P31213 1/20 0.49
DUSP3 P51452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloro-Benzoic Acid SCHEMBL9317543 0.97 TAS2R38 (0.59) TAS2R38ALDH1A1CYP19A1ALOX15TSHR
4-Chloro-Benzoic Acid SCHEMBL9316889 0.85 TAS2R38 (0.56) TAS2R38ALDH1A1CYP19A1NPC1RAB9A
4-Chloro-Benzoic Acid SCHEMBL9317547 0.85 TAS2R38 (0.56) TAS2R38ALDH1A1CYP19A1NPC1RAB9A
4-Chloro-Benzoic Acid SCHEMBL9317094 0.84 ALDH1A1 (0.58) ALDH1A1CYP19A1ALOX15TSHRNPC1
SCHEMBL2344103 0.83 ALDH1A1 (0.63) TAS2R38ALDH1A1TSHRNPC1RAB9A
4-Chloro-Benzoic Acid SCHEMBL9317407 0.81 ALDH1A1 (0.58) ALDH1A1ALOX15TSHRNPC1RAB9A
SCHEMBL10189868 0.77 EPHX1 (0.60) TAS2R38ALDH1A1TSHRNPC1RAB9A
SCHEMBL340780 0.77 TAS2R38 (1.00) TAS2R38ALDH1A1TSHRNPC1RAB9A
4-Chloro-Benzoic Acid SCHEMBL6444124 0.75 TSHR (0.85) ALDH1A1ALOX15TSHRNPC1RAB9A
SCHEMBL4101962 0.75 TAS2R38 (0.95) TAS2R38ALDH1A1TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354514-A Heating mixture of thioamide compound and copper- or lead-containing compound JUJO PAPER CO., LTD. (JP) 1994-10-11 US disclosed