SCHEMBL340780

SCHEMBL340780

CC(=S)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R38 P59533 3/20 1.00
HSD17B10 Q99714 3/20 0.65
ALDH1A1 P00352 3/20 0.65
TP53 P04637 2/20 0.65
TSHR P16473 2/20 0.65
TYR P14679 1/20 0.65
CYP3A4 P08684 1/20 0.64
GAA P10253 5/20 0.58
KMT2A Q03164 4/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
MEN1 O00255 1/20 0.58
NOX1 Q9Y5S8 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
MAPT P10636 3/20 0.57
EPHX1 P07099 2/20 0.57
KDM4E B2RXH2 1/20 0.57
HPGD P15428 1/20 0.57
PHGDH O43175 1/20 0.56
MAOA P21397 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101962 0.97 TAS2R38 (0.95) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL31110551 0.97 TAS2R38 (0.95) TAS2R38HSD17B10ALDH1A1TP53TSHR
Phosphonic Acid SCHEMBL9435620 0.89 TAS2R38 (0.79) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL14511451 0.86 TAS2R38 (0.75) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL201794 0.81 ALDH1A1 (0.67) TAS2R38ALDH1A1CYP3A4GAAKMT2A
Acrylamide SCHEMBL11027613 0.81 TAS2R38 (0.66) TAS2R38HSD17B10ALDH1A1TP53TSHR
Phenylthiourea SCHEMBL42753 0.79 ALDH1A1 (1.00) TAS2R38HSD17B10ALDH1A1TP53TSHR
Phenylthiourea SCHEMBL11820844 0.79 ALDH1A1 (1.00) TAS2R38HSD17B10ALDH1A1TP53TSHR
Phenylthiourea SCHEMBL7814239 0.78 ALDH1A1 (0.86) TAS2R38HSD17B10ALDH1A1TP53TSHR
SCHEMBL28051724 0.78 TAS2R38 (0.63) TAS2R38HSD17B10ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 733 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
CN-118063390-A Diamine with naphthyridone structure, thermosetting polyimide resin and preparation method thereof 西北工业大学 2024-05-24 CN claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
US-4316967-A EPOXIDIZED VINYL POLYMERS ENDCAPPED WITH POLYISOLYANATES OR POLYISOTHIOCYANTES THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-02-23 US claimed
US-4299932-A ADDITION-CONDENSATION COPOLYMER OF A HYDROLYSED ISOCYANATE-AMIDE-MODIFIED DIENE, POLYURETHANE, AND POLYUREA THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-10 US claimed
US-4298707-A ADDITION-CONDENSATION POLYMER FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-03 US claimed
US-4239860-A REACTING AMINE-TERMINATED ADDITION POLYMER WITH POLYURETHANE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-16 US claimed
US-4235979-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-11-25 US claimed
US-4157430-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-06-05 US claimed
US-4155947-A Amine terminated polymers and the formation of blocked copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-22 US claimed
US-4155948-A Amine terminated polymers and the formation of blocked copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-22 US claimed
US-4151222-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-04-24 US claimed
US-4070344-A WITH POLYISOCYANATE, AMIDE, HYDROLYSIS THE FIRESTONE TIRE AND RUBBER COMPANY (US) 1978-01-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 TAS2R38 569/4885HSD17B10 1036/4885ALDH1A1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.