SCHEMBL9317088

SCHEMBL9317088

C=CC(=O)OCCCCCCN(C)c1ccc(N=Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.41
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.37
CA12 O43570 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LSS P48449 2/20 0.34
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317085 1.00 MMP14 (0.41) MMP14ALDH1A1TSHRCYP3A4THRB
SCHEMBL9661188 0.92 THRB (0.40) MMP14ALDH1A1TSHRTHRBCA12
SCHEMBL9661193 0.92 THRB (0.40) MMP14ALDH1A1TSHRTHRBCA12
SCHEMBL9317451 0.89 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4THRBMAPT
SCHEMBL9317458 0.89 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4THRBMAPT
SCHEMBL9317777 0.89 MMP14 (0.41) MMP14ALDH1A1TSHRCYP3A4THRB
SCHEMBL9317768 0.89 MMP14 (0.41) MMP14ALDH1A1TSHRCYP3A4THRB
SCHEMBL9317009 0.86 MMP14 (0.41) MMP14ALDH1A1TSHRCA12CA2
SCHEMBL9317012 0.86 MMP14 (0.41) MMP14ALDH1A1TSHRCA12CA2
SCHEMBL9317473 0.83 THRB (0.53) ALDH1A1TSHRCYP3A4THRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed