SCHEMBL9317141

SCHEMBL9317141

C=C(C)C(=O)OCCN(C)c1ccc(N=Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP14 P50281 1/20 0.39
CA12 O43570 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
F2 P00734 3/20 0.38
PRSS1 P07477 2/20 0.37
PRSS2 P07478 2/20 0.37
PRSS3 P35030 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 3/20 0.35
CYP2D6 P10635 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317136 1.00 MMP14 (0.39) MMP14CA12CA2CA9F2
SCHEMBL9317012 0.92 MMP14 (0.41) MMP14CA12CA2CA9F2
SCHEMBL9317009 0.92 MMP14 (0.41) MMP14CA12CA2CA9F2
SCHEMBL9661489 0.88 CA12 (0.40) MMP14CA12CA2CA9F2
SCHEMBL9661479 0.88 CA12 (0.40) MMP14CA12CA2CA9F2
SCHEMBL16437137 0.88 POLB (0.40) MMP14CA12CA2CA9F2
SCHEMBL9317586 0.87 CTDSP1 (0.39) MMP14F2L3MBTL1POLBMEN1
SCHEMBL9317582 0.87 CTDSP1 (0.39) MMP14F2L3MBTL1POLBMEN1
SCHEMBL9661193 0.85 THRB (0.40) MMP14CA12CA2CA9F2
SCHEMBL9661188 0.85 THRB (0.40) MMP14CA12CA2CA9F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed