SCHEMBL9317586

SCHEMBL9317586

C=C(C)C(=O)OCCN(C)c1ccc(C=Cc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC1 Q13547 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
F2 P00734 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 1/20 0.36
KCNH2 Q12809 1/20 0.36
HDAC6 Q9UBN7 1/20 0.35
RELA Q04206 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317582 1.00 CTDSP1 (0.39) CTDSP1ALDH1A1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317170 0.92 POLB (0.40) CTDSP1ALDH1A1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317175 0.92 POLB (0.40) CTDSP1ALDH1A1HDAC8HDAC1SMN1; SMN2
SCHEMBL9846841 0.88 MAOB (0.36) CTDSP1ALDH1A1KMT2AMEN1POLB
SCHEMBL9317141 0.87 MMP14 (0.39) ALDH1A1SMN1; SMN2GAAMAPTKMT2A
SCHEMBL9317136 0.87 MMP14 (0.39) ALDH1A1SMN1; SMN2GAAMAPTKMT2A
SCHEMBL9317354 0.86 ALDH1A1 (0.44) CTDSP1ALDH1A1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317356 0.86 ALDH1A1 (0.44) CTDSP1ALDH1A1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317030 0.81 POLB (0.48) ALDH1A1GAAMAPTKMT2AMEN1
SCHEMBL9317026 0.81 POLB (0.48) ALDH1A1GAAMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed