SCHEMBL9317645

SCHEMBL9317645

C=CC(=O)OCCSc1ccc(N=Nc2ccc(S(C)(=O)=O)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.38
THRB P10828 1/20 0.35
TSHR P16473 5/20 0.34
CA2 P00918 5/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA7 P43166 2/20 0.34
CA13 Q8N1Q1 2/20 0.34
HPGD P15428 1/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
CYP3A4 P08684 1/20 0.33
DAO P14920 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AKR1C3 P42330 1/20 0.33
CDK1 P06493 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317640 1.00 TGM2 (0.38) TGM2THRBTSHRCA2CA12
SCHEMBL9318783 0.91 TSHR (0.42) TGM2THRBTSHRCA2CA12
SCHEMBL9318778 0.91 TSHR (0.42) TGM2THRBTSHRCA2CA12
SCHEMBL9317758 0.86 TGM2 (0.39) TGM2THRBAKR1C3
SCHEMBL9317756 0.86 TGM2 (0.39) TGM2THRBAKR1C3
SCHEMBL9317411 0.86 THRB (0.42) THRBTSHRCA2CA12CA1
SCHEMBL9317406 0.86 THRB (0.42) THRBTSHRCA2CA12CA1
SCHEMBL9317079 0.83 CA2 (0.34) THRBTSHRCA2CA12CA1
SCHEMBL9317074 0.83 CA2 (0.34) THRBTSHRCA2CA12CA1
SCHEMBL9769527 0.82 MMP13 (0.32) THRBTSHRCA2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed