Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1R15A | O75807 | 1/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.46 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759611 | 0.82 | ALDH1A1 (0.50) | L3MBTL1TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL5584500 | 0.80 | ALDH1A1 (0.44) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL2355528 | 0.79 | PPP1R15A (0.43) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL20764908 | 0.79 | GAA (0.35) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL2355534 | 0.79 | PPP1R15A (0.43) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL3302004 | 0.79 | PPP1R15A (0.48) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL16955499 | 0.76 | PPP1R15A (0.41) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL8379850 | 0.75 | LMNA (0.41) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL16951865 | 0.75 | SMN1; SMN2 (0.47) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 | |
| SCHEMBL16951940 | 0.75 | L3MBTL1 (0.50) | PPP1R15AMELKPPP1R15BNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376684-A | Aminobutyric acid antagonist; antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |