Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544446 | 0.78 | HTT (0.45) | ALDH1A1 | |
| SCHEMBL9313939 | 0.76 | ALOX5 (0.50) | ALDH1A1 | |
| SCHEMBL7314770 | 0.76 | TSHR (0.45) | ALDH1A1MAPT | |
| SCHEMBL8550091 | 0.75 | MEN1 (0.38) | ALDH1A1 | |
| SCHEMBL8544494 | 0.74 | GABRP (0.48) | ALDH1A1MAPT | |
| SCHEMBL7303326 | 0.73 | ALOX5 (0.38) | — | |
| SCHEMBL7441078 | 0.73 | KDM4E (0.34) | ALDH1A1 | |
| SCHEMBL9318021 | 0.73 | ALOX5 (0.44) | — | |
| SCHEMBL9434971 | 0.70 | KDM4E (0.47) | ALDH1A1MAPT | |
| SCHEMBL9312203 | 0.70 | AGTR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317023-A | 2-Phenyl-(imidazo(4,5-b)pyridyl-methyl-) derivatives; hypertensive agents; cognition activators | GLAXO GROUP LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |