Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544320 | 0.83 | KDM4E (0.63) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL9434976 | 0.81 | KDM4E (0.38) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL9318622 | 0.80 | KDM4E (0.47) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL8548832 | 0.76 | KDM4E (0.44) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL9318354 | 0.75 | KDM4E (0.45) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL9318281 | 0.70 | ALDH1A1 (0.40) | MAPTALDH1A1 | |
| SCHEMBL5106474 | 0.69 | S1PR4 (0.50) | KDM4EMAPTRAB9AHPGDNPC1 | |
| SCHEMBL7312942 | 0.69 | KDM4E (0.62) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL9663251 | 0.68 | HSP90AA1 (0.41) | KDM4EPOLBMAPTRAB9AHPGD | |
| SCHEMBL2206554 | 0.67 | ADORA3 (0.50) | KDM4EPOLBHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011369-A1 | ANTIHYPERTENSIVE 5-[(IMIDAZO[4,5-b]PYRIDIN-3-YL)METHYL]BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |