SCHEMBL9318602

SCHEMBL9318602

CCCCCCCCCCC(C(=O)O)S(=O)(=O)c1ccccc1S(=O)(=O)CCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.42
CYSLTR1 Q9Y271 2/20 0.42
FFAR4 Q5NUL3 1/20 0.40
FFAR1 O14842 1/20 0.40
APEX1 P27695 1/20 0.39
EPHX2 P34913 1/20 0.39
HDAC8 Q9BY41 4/20 0.37
HDAC3 O15379 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
PPARG P37231 3/20 0.37
PPARD Q03181 3/20 0.37
PPARA Q07869 3/20 0.37
TSHR P16473 2/20 0.37
GPR84 Q9NQS5 2/20 0.37
HDAC11 Q96DB2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7784104 0.82 CA12 (0.43) FFAR1HDAC8HDAC3HDAC6MMP2
SCHEMBL9318572 0.81 CYSLTR2 (0.47) CYSLTR2CYSLTR1HDAC6PPARGPPARA
SCHEMBL9754526 0.76 MMP9 (0.54) FFAR1MMP2MMP9MMP12GPR84
SCHEMBL12933668 0.76 MMP9 (0.54) FFAR1MMP2MMP9MMP12GPR84
SCHEMBL1890167 0.72 MMP9 (0.37) HDAC8HDAC3HDAC6MMP2MMP9
SCHEMBL5592398 0.72 MMP2 (0.43) MMP2MMP9MMP12ALDH1A1MEN1
SCHEMBL7619142 0.71 TSHR (0.53) TSHRTDP1ALDH1A1ALOX15
SCHEMBL27182979 0.70 MMP13 (0.57) MMP2MMP9MMP12TDP1
SCHEMBL7784108 0.69 APEX1 (0.50) APEX1HDAC8HDAC3HDAC6HDAC1
SCHEMBL7825144 0.69 MMP9 (0.55) FFAR1MMP2MMP9TSHRGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576603-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO. INC. (US) 1994-01-05 EP disclosed