SCHEMBL1890167

SCHEMBL1890167

CCCCCCCCCC(C(=O)O)S(=O)(=O)c1ccc(N)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 4/20 0.37
MMP13 P45452 2/20 0.37
ADAM17 P78536 2/20 0.37
MMP1 P03956 2/20 0.37
MMP2 P08253 5/20 0.36
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
CTRC Q99895 1/20 0.36
CSNK1E P49674 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HDAC8 Q9BY41 4/20 0.36
HDAC3 O15379 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
MMP12 P39900 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8836457 0.88 MMP2 (0.41) MMP9MMP2
SCHEMBL10765755 0.79 TTR (0.41) HDAC3
SCHEMBL7784104 0.78 CA12 (0.43) MMP9MMP13ADAM17MMP1MMP2
SCHEMBL12933668 0.77 MMP9 (0.54) MMP9MMP13ADAM17MMP1MMP2
SCHEMBL9754526 0.77 MMP9 (0.54) MMP9MMP13ADAM17MMP1MMP2
SCHEMBL4509390 0.76 CYP1A2 (0.53) HDAC3HDAC6HDAC1HDAC2
SCHEMBL1168298 0.75 MMP2 (0.46) MMP9MMP2MMP12
SCHEMBL28046230 0.73 TTR (0.45) HDAC3
SCHEMBL4506081 0.72 KYNU (0.44) GRIK1
SCHEMBL9318602 0.72 CYSLTR2 (0.42) MMP9MMP2ALDH1A1HDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114462-B1 Compounds for fluorescence imaging UNIV GENEVE (CH) 2013-06-05 EP claimed
US-20100278745-A1 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (CH) 2010-11-04 US claimed
EP-2114462-A2 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (CH) 2009-11-11 EP claimed
WO-2008078190-A2 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (US) 2008-07-03 WO claimed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 EP disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-10345310-B2 Diagnostic test for early stage cancer THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-07-09 US disclosed
EP-3307243-A1 DIAGNOSTIC TEST FOR EARLY STAGE CANCER The Board of Regents of The University of Texas System (US) 2018-04-18 EP disclosed
US-20170146542-A1 DIAGNOSTIC TEST FOR EARLY STAGE CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-05-25 US disclosed
WO-2016201064-A1 DIAGNOSTIC TEST FOR EARLY STAGE CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-12-15 WO disclosed
EP-2114462-B1 Compounds for fluorescence imaging UNIV GENEVE (CH) 2013-06-05 EP disclosed
US-20100278745-A1 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (CH) 2010-11-04 US disclosed
US-20100233782-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2010-09-16 US disclosed
EP-2118129-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2009-11-18 EP disclosed
EP-2114462-A2 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (CH) 2009-11-11 EP disclosed
US-20090161828-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES LIFE TECHNOLOGIES (US) 2009-06-25 US disclosed
US-20080248565-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-10-09 US disclosed
WO-2008106660-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-09-04 WO disclosed
WO-2008078190-A2 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (US) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR MMP9 2321/4885MMP13 1332/4885ADAM17 1472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.