SCHEMBL9319115

SCHEMBL9319115

CC1=CC(C)C([SiH](Cc2ccccc2)C2=C(C)C(C)=CC2C)=C1C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048682 0.71
SCHEMBL8992234 0.61 CALM1 (0.43) TP53
SCHEMBL6960735 0.58 TP53 (0.48) TP53
SCHEMBL476128 0.58 TP53 (0.48) TP53
SCHEMBL703318 0.58 TP53 (0.48) TP53
SCHEMBL41196 0.57 CALM1 (0.50) TP53
Fluoride SCHEMBL28075257 0.57 TP53 (0.46) TP53
Hydrochloric Acid SCHEMBL29160220 0.56 CALM1 (0.47) TP53
SCHEMBL9422248 0.56 CALM1 (0.47) TP53
Fluoride SCHEMBL27669418 0.56 CALM1 (0.47) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5360921-A REACTING LITHIUM, SODIUM OR POTASSIUM SALT OF A CYCLOPENTADIENE DERIVATIVE WITH A SILICON OR GERMANIUM HALIDE COMPOUND IN THE PRESENCE OF A CYANIDE OR A THIOCYANATE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-11-01 US disclosed
EP-0617044-A2 Process for preparing cyclopentadienyl group-containing silicon compound or cyclopentadienyl group-containing germanium compound MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-09-28 EP disclosed