Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319068 | 0.80 | ELANE (0.41) | MGLLMAPTALOX5MEN1KMT2A | |
| SCHEMBL9855189 | 0.72 | L3MBTL1 (0.53) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 | |
| SCHEMBL28424953 | 0.70 | MGLL (0.61) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 | |
| SCHEMBL9320296 | 0.70 | KMT2A (0.46) | L3MBTL1MGLLMAPTALOX5MEN1 | |
| SCHEMBL259385 | 0.68 | L3MBTL1 (1.00) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 | |
| SCHEMBL22423676 | 0.67 | HSP90AA1 (0.47) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 | |
| SCHEMBL16291450 | 0.67 | MEN1 (0.41) | MGLLMAPTMEN1KMT2AGAA | |
| SCHEMBL9644524 | 0.67 | ALOX5 (0.51) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 | |
| SCHEMBL17503368 | 0.66 | ALDH1A1 (0.49) | L3MBTL1HSP90AA1MGLLHSD17B10MEN1 | |
| SCHEMBL8121918 | 0.66 | L3MBTL1 (0.68) | L3MBTL1HSP90AA1MGLLMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267277-B1 | COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS | WHITBY RESEARCH INC (US) | 1994-01-19 | — | — | EP | disclosed |
| EP-0325613-B1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | WHITBY RESEARCH, Inc. (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5142044-A | Lactam derivatives | WHITBY RESEARCH, INC. (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0267277-A4 | COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. | NELSON RES & DEV COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4801586-A | N-HETEROCYCLES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-01-31 | — | — | US | disclosed |
| US-4755535-A | Compositions comprising 1-substituted azacycloalkenes | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0267277-A1 | COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS. | NELSON RES & DEV (US) | 1988-05-18 | — | — | EP | disclosed |
| WO-1987006583-A1 | COMPOSITIONS COMPRISING 1-SUBSTITUTED LACTAMS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1987-11-05 | — | — | WO | disclosed |