Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319851 | 1.00 | HPGD (0.37) | HPGDKDM4EALDH1A1POLBCASP6 | |
| SCHEMBL990076 | 0.87 | KDM4E (0.40) | HPGDKDM4EALDH1A1POLBCASP6 | |
| SCHEMBL29366932 | 0.87 | KDM4E (0.40) | HPGDKDM4EALDH1A1POLBCASP6 | |
| SCHEMBL28806661 | 0.87 | KDM4E (0.40) | HPGDKDM4EALDH1A1POLBCASP6 | |
| SCHEMBL7422383 | 0.87 | ATM (0.38) | HPGDKDM4EALDH1A1CYP2C9TSHR | |
| SCHEMBL7422369 | 0.87 | ATM (0.38) | HPGDKDM4EALDH1A1CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL6994200 | 0.86 | ALDH1A1 (0.39) | HPGDKDM4EALDH1A1POLBCASP6 | |
| SCHEMBL11551373 | 0.80 | KDM4E (0.30) | HPGDKDM4EALDH1A1 | |
| SCHEMBL11556600 | 0.77 | MAOA (0.32) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11786875 | 0.75 | CYP2B6 (0.34) | HPGDKDM4EALDH1A1POLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288731-A | Antiemetics, antiserotonine agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-02-22 | — | — | US | disclosed |