Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319939 | 0.75 | ALDH1A1 (0.42) | KDM4EHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL9840700 | 0.72 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL9321255 | 0.68 | LMNA (0.51) | SRCKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9424928 | 0.66 | LMNA (0.41) | SRCKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3002686 | 0.66 | PTPN1 (0.40) | KDM4EHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL9318828 | 0.65 | KDM4E (0.65) | KDM4EHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL29168929 | 0.64 | CTSK (0.39) | KDM4EMAPTCA1CA2CA9 | |
| SCHEMBL29168933 | 0.64 | CTSK (0.39) | KDM4EMAPTCA1CA2CA9 | |
| SCHEMBL23515051 | 0.64 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1HSD17B10TSHR | |
| SCHEMBL14845162 | 0.64 | KDM4E (0.57) | KDM4EHPGDALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |